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Silo Pharma Initiates Research of Novel Joint Homing Peptide in Human Tissue

Silo Pharma, Inc.

Preliminary information from research anticipated in first quarter 2023

ENGLEWOOD CLIFFS, NJ, Nov. 21, 2022 (GLOBE NEWSWIRE) — Silo Pharma, Inc. (Nasdaq: SILO) (“the Firm”), A developmental stage biopharmaceutical firm centered on merging conventional therapeutics with psychedelic analysis, immediately introduced its plans to provoke a pilot research of its novel joint homing peptides focusing on rheumatoid arthritis (RA), designated as SPU-21, in human synovial tissue surrounding joints and tendons . The three-month research will assess the binding affinity of the peptide in wholesome human and RA synovial tissue. Preliminary information from the research is predicted through the first quarter of 2023.

“SPU-21 was proven to inhibit arthritic development in a preclinical animal mannequin, so we’re continuing to advance our analysis into human synovial tissue, the place we are going to first assess binding affinity,” mentioned Eric Weisblum, Chief Govt Officer of Silo Pharma. “Optimistic information from this essential research might help additional analysis into the interplay of our joint homing peptide as a possible remedy for autoimmune problems comparable to rheumatoid arthritis and irritation. We sit up for progressing our growth of SPU-21 by our valued collaboration with the College of Maryland, Baltimore.”

Underneath a business analysis license and choice settlement with the College of Maryland, Baltimore (UMB), Silo Pharma is advancing the event of UMB’s liposomal homing peptide to ship focused therapeutics that would embrace psilocybin. The confirmed means of the peptide to focus on infected epithelium counsel they may very well be used to focus on drug supply. This strategy might improve the therapeutic impact of present and future therapies and reduce potential systemic toxicity regardless of systemic administration of the drug. The peptides even have potential for the event of fusion imaging molecules and/or nanoparticles to check arthritic pathogenesis, may very well be customizable for potential use in delivering nanoparticles for exact imaging, and can be utilized to deal with autoimmune illnesses, together with however not restricted to RA.

Rheumatoid arthritis is among the many commonest autoimmune illnesses within the US, affecting roughly 1.5 People. A 2022 report printed by Priority Analysis states that the worldwide rheumatoid arthritis medication market is predicted to succeed in $70 billion by 2030, rising at a compound annual development price of 1.7%.1

Along with SPU-21, Silo Pharma holds a license settlement with UMB for a central nervous system (CNS) homing peptide for the investigation and remedy of a number of sclerosis and different uncommon neurological illnesses designated as SPU-16.

About Silo Pharma

Silo Pharma. Inc. is a development-stage biopharmaceutical firm centered on merging conventional therapeutics with psychedelic analysis for folks affected by indications comparable to PTSD, Alzheimer’s illness, and different uncommon neurological problems. Silo’s mission is to establish property to license and fund the analysis which we imagine might be transformative to the well-being of sufferers and the healthcare business. For extra data, go to

Ahead-Wanting Statements

All statements apart from statements of historic reality on this announcement are forward-looking statements that contain identified and unknown dangers and uncertainties and are based mostly on present expectations and projections about future occasions and monetary tendencies that the Firm believes could have an effect on its monetary situation, outcomes of operations, enterprise technique, and monetary wants. Traders can establish these forward-looking statements by phrases or phrases comparable to “could,” “will,” “count on,” “anticipate,” “intention,” “estimate,” “intend,” “plan,” “imagine,” “potential,” “proceed,” “is/are more likely to” or different related expressions. The Firm undertakes no obligation to replace forward-looking statements to replicate subsequent occurring occasions or circumstances, or modifications in its expectations, besides as could also be required by legislation. Though the Firm believes that the expectations expressed in these forward-looking statements are cheap, it can not guarantee you that such expectations will turn into right, and the Firm cautions traders that precise outcomes could differ materially from the anticipated outcomes and encourages traders to evaluate different elements which will have an effect on its future ends in the Firm’s filings with the SEC.


1 Priority Analysis; Rheumatoid Arthritis Medication Market, Report 2022-2030. June 2022.

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